01 - Combine cranberries, orange juice, sugar, orange zest, and salt in a small saucepan. Simmer over medium heat, stirring occasionally, until cranberries burst and sauce thickens, about 8 to 10 minutes. Remove from heat and cool.
02 - In a large bowl, gently mix ground turkey, onion, garlic, parsley, Dijon mustard, Worcestershire sauce, salt, pepper, and breadcrumbs until just combined. Form mixture into 4 equal patties.
03 - Heat olive oil in a large skillet over medium heat. Cook patties 5 to 6 minutes per side, or until golden brown and internal temperature reaches 165°F (74°C).
04 - Lightly toast burger buns if desired.
05 - Layer lettuce on bottom bun halves, place turkey patties on top. Spoon cranberry sauce over patties, then add sliced tomatoes and red onion. Cover with top bun halves.
06 - Serve immediately, with extra cranberry sauce on the side if preferred.